Material Safety Data Sheet: 1-Chlorooctane

1. Identification

Product Name: 1-Chlorooctane
Synonyms: Octyl chloride, n-Octyl chloride
CAS Number: 111-85-3
Recommended Use: Chemical intermediate, laboratory reagent
Manufacturer: Refer to supplier contact information
Emergency Phone: Local emergency services or regional poison control center

2. Hazard Identification

GHS Classification: Flammable Liquids, Category 3; Acute Toxicity, Oral Category 4; Skin Irritant, Category 2; Eye Irritant, Category 2A; Specific Target Organ Toxicity—Single Exposure, Category 3
Label Elements: Pictograms (exclamation mark, flame)
Signal Word: Warning
Hazard Statements: Harmful if swallowed. Causes skin and eye irritation. May cause respiratory irritation. Flammable liquid and vapor.
Precautionary Statements: Keep away from heat, sparks, open flames, hot surfaces. Wear protective gloves, eye protection, and face protection. Avoid breathing vapor. Wash thoroughly after handling.
Routes of Exposure: Inhalation, skin contact, ingestion, eye contact
Adverse Human Health Effects: Respiratory tract irritation, central nervous system effects may follow significant exposure through inhalation.

3. Composition / Information on Ingredients

Chemical Identity: 1-Chlorooctane
Molecular Formula: C8H17Cl
Molecular Weight: 148.68 g/mol
Concentration: 98% or above as supplied
Impurities: Other chloroalkanes (trace)
EC Number: 203-914-1
Dangerous Components: No significant other hazardous ingredients identified in pure material

4. First Aid Measures

General Notes: Ensure your own safety before assisting others. Remove from exposure site.
Inhalation: Move to fresh air. Seek medical attention for symptoms like coughing, wheezing, dizziness.
Skin Contact: Wash with plenty of soap and water. Remove contaminated clothing. Seek medical attention for persistent irritation.
Eye Contact: Rinse with water for several minutes. Remove contact lenses. Seek medical assistance if irritation persists.
Ingestion: Do not induce vomiting. Rinse mouth with water, seek medical help immediately.
Note to Physician: Symptomatic and supportive treatment recommended. Monitor for respiratory distress.

5. Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, alcohol-resistant foam
Unsuitable Media: Strong water jet may spread the liquid
Specific Hazards: Vapors may form explosive mixture with air. Releases hydrogen chloride, carbon monoxide, carbon dioxide upon combustion.
Protective Equipment: Self-contained breathing apparatus and full protective clothing.
Firefighting Instructions: Evacuate area, fight fire from a safe distance, use water to cool surrounding containers.
Explosion Data: Vapors heavier than air, accumulate in low areas and travel to remote sources of ignition.

6. Accidental Release Measures

Personal Precautions: Evacuate unprotected personnel. Avoid contact with skin, eyes, clothing. Wear chemical splash goggles, gloves, and respirator.
Environmental Precautions: Prevent spillage from reaching drains, surface waters, or soil.
Containment: Cover with inert absorbent material (sand, earth, vermiculite), ventilate area.
Cleanup Methods: Shovel absorbed material into appropriate waste container for disposal in accordance with regulations. Wash spill area with detergent and water.
Disposal: See section on Disposal Considerations for safe handling of waste material.

7. Handling and Storage

Handling: Use only in well-ventilated areas. Avoid vapor formation and contact with ignition sources. Wear appropriate PPE at all stages of handling. Do not eat or drink in work area.
Storage: Store in a tightly closed container, in a cool, dry, well-ventilated location. Segregate from oxidizers, acids, and sources of ignition. Keep container upright, away from direct sunlight, moisture.

8. Exposure Controls and Personal Protection

Occupational Exposure Limits: No established specific national limits for 1-Chlorooctane. Follow general solvent limits where applicable.
Engineering Controls: Local exhaust ventilation, general dilution ventilation. Explosion-proof electrical equipment recommended.
Personal Protection Equipment: Chemical-resistant gloves (nitrile, neoprene), protective clothing (lab coat, apron), goggles or face shield.
Respiratory Protection: If vapor concentration exceeds limits, use an organic vapor respirator or supplied air system.
Hygiene: Wash hands after handling, remove contaminated clothing, change into clean clothes after exposure.

9. Physical and Chemical Properties

Appearance: Clear, colorless to pale yellow liquid
Odor: Mild, sweet, chloroalkane-like
Odor Threshold: No data available
pH: Not applicable
Melting Point: -51°C
Boiling Point: 179°C
Flash Point: 54°C (Closed cup)
Evaporation Rate: No data available
Flammability: Flammable liquid
Upper/Lower Explosion Limits: Data not available, assume vapors form explosive mixtures
Vapor Pressure: 1.3 mm Hg @ 25°C
Vapor Density: 5.1 (Air = 1)
Relative Density: 0.866 g/cm³ @ 25°C
Solubility: Slightly soluble in cold water; soluble in organic solvents
Partition Coefficient (log Kow): Approx. 4.4
Autoignition Temperature: 320°C
Decomposition Temperature: Data not available
Viscosity: No data available

10. Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling.
Reactivity: No dangerous reactions expected under normal use.
Possibility of Hazardous Reactions: Contact with strong oxidizing agents may yield violent reaction.
Conditions to Avoid: Heating, open flames, sparks, sources of static discharge.
Incompatible Materials: Strong bases, strong oxidizers, alkali metals.
Hazardous Decomposition Products: Hydrogen chloride, carbon monoxide, phosgene in fire situation.

11. Toxicological Information

Acute Toxicity (Oral): LD50 (rat): 200–2000 mg/kg (based on similar alkyl chlorides)
Inhalation Exposure: May cause dizziness, headache, central nervous system depression
Skin Corrosion/Irritation: Causes irritation; prolonged contact may worsen effects
Eye Damage/Irritation: Causes irritation, redness, tearing
Skin Sensitization: Not expected, though repeated exposure may develop dermatitis
Germ Cell Mutagenicity: No available data
Carcinogenicity: Not listed by ACGIH, IARC, NTP or OSHA
Reproductive Toxicity: No specific information, avoid exposure as a precaution
Target Organ Effects: Central nervous system, digestive tract, skin, eyes
Chronic Toxicity: Prolonged or repeated exposure may lead to liver and kidney effects as with other chloroalkanes

12. Ecological Information

Ecotoxicity: Potentially toxic to aquatic life. Limited data, but similar chloroalkanes show acute toxicity to fish and invertebrates in low concentrations.
Persistence and Degradability: Not readily biodegradable. Can persist in environment and bioaccumulate.
Bioaccumulative Potential: High log Kow indicates significant potential for bioaccumulation.
Mobility in Soil: Low to moderate mobility; volatilizes slowly from soil surfaces, may leach in sandy soils.
Other Adverse Effects: Ozone depletion not anticipated; avoid release to environment and watercourses.

13. Disposal Considerations

Disposal Methods: Small quantities—absorb on inert material, incinerate at licensed facility. Large spills—collect for proper recovery or disposal.
Waste Code: Consult local, state, or national regulations for appropriate waste classification.
Packaging Disposal: Rinse containers thoroughly before disposal. Do not reuse empty containers, send to approved waste handler.
Environmental Precautions: Prevent product or rinse water from entering waterways.
Special Considerations: Consult chemical waste professionals for best practices.

14. Transport Information

UN Number: UN1993
Proper Shipping Name: Flammable liquids, n.o.s. (contains 1-Chlorooctane)
Transport Hazard Class: 3 (Flammable Liquid)
Packing Group: III
Environmental Hazards: Not considered marine pollutant at normal quantities, but spills can be hazardous
Special Transport Precautions: Segregate from foodstuffs, acids, oxidizers. Secure container for transit to avoid leakage.

15. Regulatory Information

US EPA: Not listed under CERCLA or EPCRA. May be subject to SARA Section 311/312 for immediate health and fire hazards.
TSCA Status: Listed
EU Regulations: CLP classification applies as flammable, irritant. EC Inventory listed.
Canada: DSL/NDSL listed.
Other Global Inventories: Australia (AICS), China (IECSC), Japan (ENCS), Korea (ECL), Philippines (PICCS), New Zealand (NZIoC) listed.
Label Requirements: Follow workplace safety and environment hazardous chemical labeling standards.
Workplace Restrictions: Only professionally trained personnel should handle bulk material.